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Case Studies: OCD/POTS: Kristen, 235, 237-239
Ferritin, See Iron/Ferritin
Folate Receptor Antibody (FRAT), See Cerebral Folate Deficiency (CFD)
Folinic acid (See 5-methyltetrahydrofolate (MTHF/5-MeTHF/Folinic acid))
Flavonoids (Quercetin, Luteolin, Rutin)
Immunotherapy: Inflammation, 103, 105, 108
Case Studies: Autism and HDCs: Ty, 257
Fluconazole
Meet the Infectious Agents: Yeast Dysbiosis, 56
Fluoxetine (See SSRIs)
Food allergies/sensitivities
Immunotherapy: Inflammation, 104
Immunotherapy: Nutrition, 125, 127
Symptom-Specific Treatment: Tics, 143, 144
Gabapentin
Immunotherapy: Inflammation, 105, 109
Gamma-aminobutyric Acid (GABA)
Immunotherapy: Inflammation, 109
Immunotherapy: Nutrition, 124, 125
Symptom-Specific Treatment: Anxiety, 134
Symptom-Specific Treatment: Tics, 140, 141
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 154
Symptom-Specific Treatment: Sleep, 168
Garlic (See Allicin/Allium/Garlic)
Ginger
Immunotherapy: Inflammation, 104
Immunotherapy: The Addition of Antioxidants, 118
Immunotherapy: Nutrition, 121
Glutamate
Meet the Infectious Agents: Mold and Chronic Inflammatory Response Syndrome (CIRS), 66
287
Demystifying PANS/PANDAS
Eradicate the Pathogens: All About Antimicrobials, 87
Immunotherapy: Nutrition, 124, 125
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 150
Symptom-Specific Treatment: Sleep, 168
Glutathione
Meet the Infectious Agents: Mold and Chronic Inflammatory Response Syndrome (CIRS),
64, 66
Meet the Infectious Agents: Other Infections: Parasites, Clostridia, Lyme Disease, and
Co-infections, 81
Immunotherapy: The Addition of Antioxidants, 113, 115, 117, 118
Immunotherapy: Nutrition, 123
Symptom-Specific Treatment: Tics, 140
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 153
Case Studies: Mycoplasma/OCD: Eva, 208
Case Studies: PANDAS and Mold: Hannah, 227, 228
Case Studies: Tics and Antioxidants: Caleb, 243-245
Gluten
Immunotherapy: Inflammation, 104
Immunotherapy: Nutrition, 124
Symptom-Specific Treatment: Tics, 143, 144
Case Studies: Multiple Infection PANS/PANDAS: Matt, 198
Case Studies: PANDAS, Crohn’s, and HDCs: Charlie, 247
Glycine
Case Studies: Tics and Antioxidants: Caleb, 244
Goldenseal (See Berberine)
Grapefruit Seed Extract (GSE)
Meet the Infectious Agents: Yeast Dysbiosis, 57
Eradicate the Pathogens: All About Antimicrobials, 91
Case Studies: Multiple Infections, Vitamin Deficiency, and Mycotoxins: Sofia, 218
Case Studies: Lyme, Multiple Co-Infections, and Basal Ganglia Encephalitis: Avery, 222
Case Studies: PANDAS, Crohn’s, and HDCs: Charlie, 249
Guanfacine (Intuniv)
Symptom-Specific Treatment: Tics, 141
Symptom-Specific Treatment: Brain Fog, 159
Gut and Psychology Syndrome Diet (GAPS)
Immunotherapy: Nutrition, 126
Gymnema
Eradicate the Pathogens: All About Antimicrobials, 91
288
Nancy O’Hara, MD, MPH, FAAP
Headaches
Meet the Infectious Agents: Mold and Chronic Inflammatory Response Syndrome (CIRS), 63
Immunotherapy: Inflammation, 101
Case Studies: PANDAS and Mold: Hannah, 225, 227, 228
Case Studies: OCD/POTS: Kristen, 235-240
Healing crisis, See Herxheimer/Die-Off/Healing crisis
Helminth Therapy/ Helminths/HDCs
The PANS/PANDAS Journey: Considering PANDAS, 23
Meet the Infectious Agents: Other Infections: Parasites, Clostridia, Lyme Disease, and
Co-infections, 70, 71
Immunotherapy: HDCs: Helminth Therapy, 95, 97-99
Case Studies: Multiple Infection PANS/PANDAS: Matt, 198
Case Studies: PANDAS, Mold, Babesia and Dysautonomia: Zevin, 232, 233
Case Studies: PANDAS, Crohn’s, and HDCs: Charlie, 250, 251
Case Studies: Autism and HDCs: Ty, 256, 257
Hemp (See Cannabidiols/CBD)
Herxheimer/Die-off/Healing crisis
The PANS/PANDAS Journey: Considering PANDAS, 21, 22
The PANS/PANDAS Journey: The Introduction of PANS, 30
Meet the Infectious Agents: Yeast Dysbiosis, 53, 57-59
Meet the Infectious Agents: Mold and Chronic Inflammatory Response Syndrome (CIRS), 65
Meet the Infectious Agents: Other Infections: Parasites, Clostridia, Lyme Disease, and
Co-infections, 78, 79
Immunotherapy: HDCs: Helminth Therapy, 99
Symptom-Specific Treatment: Constipation, 171
Case Studies: OCD and PANS/PANDAS: Dante, 193
Case Studies: Multiple Infection PANS/PANDAS: Matt, 199, 200
Case Studies: Autism and HDCs: Ty, 256
Holy basil
Symptom-Specific Treatment: Anxiety, 133
Homeopathy
Symptom-Specific Treatment: Tics, 147
Houttuynia
The PANS/PANDAS Journey: The Introduction of PANS, 29
Meet the Infectious Agents: Mycoplasma and PANS, 47
Eradicate the Pathogens: All About Antimicrobials, 90
5 - hydroxytryptophan (5-HTP)
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 154
289
Demystifying PANS/PANDAS
Symptom-Specific Treatment: Sleep, 168
Case Studies: PANDAS, Crohn’s, and HDCs: Charlie, 249
Hypotonia
Case Studies: Mitochondrial Dysfunction and Mycoplasma: Elijah, 211
Ibuprofen/NSAIDs
The PANS/PANDAS Journey: Considering PANDAS, 17, 23
The PANS/PANDAS Journey: The Introduction of PANS, 30
Immunotherapy: Inflammation, 109
Immunotherapy: The Addition of Antioxidants, 118
Case Studies: PANDAS/Autoimmunity: James, 189
Case Studies: Lyme, Multiple Co-Infections, and Basal Ganglia Encephalitis: Avery, 221
Case Studies: PANDAS, Mold, Babesia and Dysautonomia: Zevin, 232
Case Studies: Autism and HDCs: Ty, 256, 257
Immune tolerance
Immunotherapy: Helminth Therapy, 96
Case Studies: PANDAS, Mold, Babesia, and Dysautonomia: Zevin, 234
Case Studies: PANDAS, Crohn’s, and HDCs: Charlie, 250
Case Studies: Autism and HDCs: Ty, 256
Inflammation (including inflammatory markers such as CRP, ESR, etc.)
The PANS/PANDAS Journey: Laboratory Test List, 5
The PANS/PANDAS Journey: Considering PANDAS, 17, 19, 20, 22, 23
The PANS/PANDAS Journey: The Introduction of PANS, 30, 31, 34, 35
Meet the Infectious Agents: Mycoplasma and PANS, 47
Meet the Infectious Agents: Viruses, 50
Meet the Infectious Agents: Yeast Dysbiosis, 53, 55
Meet the Infectious Agents: Mold and Chronic Inflammatory Response Syndrome (CIRS),
61, 62, 64, 66
Meet the Infectious Agents: Other Infections: Parasites, Clostridia, Lyme Disease, and
Co-infections, 69, 78, 81
Eradicate the Pathogen: All About Antimicrobials, 90
Immunotherapy: HDCs: Helminth Therapy, 96
Immunotherapy: Inflammation, 101-103, 106-108
Immunotherapy: The Addition of Antioxidants, 113, 117, 118
Immunotherapy: Nutrition, 120, 124-127
Symptom-Specific Treatment: Anxiety. 132, 135
Symptom-Specific Treatment: Tics, 140, 141, 143
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 150, 153
Symptom-Specific Treatment: Brain Fog, 159, 160
290
Nancy O’Hara, MD, MPH, FAAP
Symptom-Specific Treatment: Sleep, 167
Symptom-Specific Treatment: Constipation, 171, 175
Symptom-Specific Treatment: Neurotherapy, 181
Case Studies: PANDAS/Autoimmunity: James, 187, 189
Case Studies: OCD and PANS/PANDAS: Dante, 191, 194
Case Studies: Autism and Mycoplasma PANS/PANDAS: Rashad, 204
Case Studies: Lyme, Multiple Co-Infections, and Basal Ganglia Encephalitis: Avery, 221
Case Studies: OCD/POTS: Kristen, 240
Case Studies: Tics and Antioxidants: Caleb, 243, 245
Case Studies: PANDAS, Crohn’s, and HDCs: Charlie, 249, 250
Case Studies: Autism and HDCs: Ty, 254, 255, 257
Case Studies: PANS and COVID: Layla, 260-263
Inositol
Symptom-Specific Treatment: Anxiety, 133
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 153
Intravenous Immunoglobulin (IVIG)/Immunoglobulins
The PANS/PANDAS Journey: Considering PANDAS, 19, 23
The PANS/PANDAS Journey: The Introduction of PANS, 30, 34
Meet the Infectious Agents: Viruses, 50
Immunotherapy: Inflammation, 110
Immunotherapy: Nutrition, 121
Case Studies: PANDAS/Autoimmunity: James, 187
Case Studies: OCD and PANS/PANDAS: Dante, 194, 195
Case Studies: Lyme, Multiple Co-Infections, and Basal Ganglia Encephalitis: Avery, 222
Case Studies: PANDAS, Mold, Babesia and Dysautonomia: Zevin, 231, 233
Case Studies: Autism and HDCs: Ty, 255
Intrusive thoughts
The PANS/PANDAS Journey: Considering PANDAS, 14
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 150
Case Studies: PANS and COVID: Layla, 260
Intuniv (See Guanfacine)
Ionophores
Meet the Infectious Agents: Mold and Chronic Inflammatory Response Syndrome (CIRS), 62
Iron/Ferritin
The PANS/PANDAS Journey: Laboratory Tests, 6
The PANS/PANDAS Journey: Considering PANDAS, 19
Immunotherapy: Inflammation,101
Immunotherapy: Nutrition, 123
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 154
Symptom-Specific Treatment: Brain Fog, 160
291
Demystifying PANS/PANDAS
Isatis
The PANS/PANDAS Journey: The Introduction of PANS, 29
Meet the Infectious Agents: Mycoplasma and PANS, 47
Eradicate the Pathogens: All About Antimicrobials, 90
Japanese knotweed
Meet the Infectious Agents: Other Infections: Parasites, Clostridia, Lyme Disease, and
Co-infections, 82
Immunotherapy: The Addition of Antioxidants, 116
Kava kava
Symptom-Specific Treatment: Sleep, 167
Lactobacillus (See Probiotics/Lactobacillus)
Lavender
Symptom-Specific Treatment: Sleep, 167
Lemon Balm
Meet the Infectious Agents: Viruses, 51
Eradicate the Pathogens: All About Antimicrobials, 91
Immunotherapy: Nutrition, 125
Symptom-Specific Treatment: Anxiety, 133
Levetiracetam
Symptom-Specific Treatment: Tics, 142
Licorice (Glycyrrhiza)
Meet the Infectious Agents: Viruses, 51
Eradicate the Pathogens: All About Antimicrobials, 91
Symptom-Specific Treatment: Anxiety, 133
Case Studies: OCD/POTS: Kristen, 240
Lithium Orotate
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 154
Lyme (Borrelia)
The PANS/PANDAS Journey: Laboratory Tests, 6
The PANS/PANDAS Journey: Considering PANDAS, 22, 24
The PANS/PANDAS Journey: The Introduction of PANS, 29, 30
Meet the Infectious Agents: Yeast Dysbiosis, 56
Meet the Infectious Agents: Mold and Chronic Inflammatory Response Syndrome (CIRS),
61, 62, 64
Meet the Infectious Agents: Other Infections: Parasites, Clostridia, Lyme Disease, and
Co-infections, 69, 73-82
292
Nancy O’Hara, MD, MPH, FAAP
Eradicate the Pathogens: All About Antimicrobials, 87, 88
Immunotherapy: Inflammation, 104
Immunotherapy: The Addition of Antioxidants, 115, 116
Symptom-Specific Treatment: Anxiety, 135
Symptom-Specific Treatment: Tics, 138
Case Studies: PANDAS/Autoimmunity: James, 187
Case Studies: OCD and PANS/PANDAS: Dante, 193, 194
Case Studies: Multiple Infection PANS/PANDAS: Matt, 197, 198, 200
Case Studies: Lyme, Multiple Co-Infections, and Basal Ganglia Encephalitis: Avery, 219,
221-223
Case Studies: PANDAS, Mold, Babesia and Dysautonomia: Zevin, 231, 233
Case Studies: Tics and Antioxidants: Caleb, 242, 243
Case Studies: Autism and HDCs: Ty, 254
Case Studies: PANS and COVID: Layla, 260
Lysine
The PANS/PANDAS Journey: Laboratory Test List, 6
Meet the Infectious Agents: Viruses, 51
Eradicate the Pathogens: All About Antimicrobials, 90
Symptom-Specific Treatment: Constipation, 173
Case Studies: Multiple Infections, Vitamin Deficiency, and Mycotoxins: Sofia, 217
Case Studies: PANS and COVID: Layla, 261
Macrolides (Azithromycin/Clarithromycin)
The PANS/PANDAS Journey: Considering PANDAS, 21
The PANS/PANDAS Journey: The Introduction of PANS, 29
Meet the Infectious Agents: Mycoplasma and PANS, 47, 48
Meet the Infectious Agents: Other Infections: Parasites, Clostridia, Lyme Disease, and
Co-infections, 78
Eradicate the Pathogens: All About Antimicrobials, 86, 87
Case Studies: PANDAS/Autoimmunity: James, 188
Case Studies: OCD and PANS/PANDAS: Dante, 193-195
Case Studies: Multiple Infection PANS/PANDAS: Matt, 199
Case Studies: Autism and Mycoplasma PANS/PANDAS: Rashad, 202-204
Case Studies: Mycoplasma/OCD: Eva, 208
Case Studies: Mitochondrial Dysfunction and Mycoplasma: Elijah, 213
Case Studies: Multiple Infections, Vitamin Deficiency, and Mycotoxins: Sofia, 217
Case Studies: Lyme, Multiple Co-Infections, and Basal Ganglia Encephalitis: Avery, 222
Case Studies: PANDAS and Mold: Hannah, 227
Case Studies: Tics and Antioxidants: Caleb, 242
293
Demystifying PANS/PANDAS
Case Studies: Autism and HDCs: Ty, 254, 255
Magnesium
The PANS/PANDAS Journey: Laboratory Test List, 5
The PANS/PANDAS Journey: Considering PANDAS, 19
Meet the Infectious Agents: Other Infections: Parasites, Clostridia, Lyme Disease, and
Co-infections, 81
Immunotherapy: Nutrition, 123, 125
Symptom-Specific Treatment: Anxiety, 133, 134
Symptom-Specific Treatment: Tics, 138, 139
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 154
Symptom-Specific Treatment: Brain Fog, 161
Symptom-Specific Treatment: Sleep, 168, 169
Symptom-Specific Treatment: Constipation, 173, 175
Case Studies: PANDAS/Autoimmunity: James, 187, 188
Case Studies: OCD and PANS/PANDAS: Dante, 193, 194
Case Studies: Autism and Mycoplasma PANS/PANDAS: Rashad, 204
Case Studies: OCD/POTS: Kristen, 237, 240
Mast Cell Mediator Disorders (MCMD)/Mast Cell Activation Syndrome (MCAS)
Immunotherapy: Inflammation, 102
Meditation/Mindfulness
Symptom-Specific Treatment: Anxiety, 134
Symptom-Specific Treatment: Tics, 146
Symptom-Specific Treatment: Obsessive-Compulsive Disorder (OCD), 155
Symptom-Specific Treatment: Neurotherapy, 177, 180
Case Studies: PANDAS/Autoimmunity: James, 188
Case Studies: OCD/POTS: Kristen, 236
Melatonin
Immunotherapy: The Addition of Antioxidants, 113, 117
Symptom-Specific Treatment: Sleep, 167, 168
Case Studies: OCD/POTS: Kristen, 239, 240
Methylation
The PANS/PANDAS Journey: Considering PANDAS, 20
Symptom-Specific Treatment: Tics, 143
Case Studies: Lyme, Multiple Co-Infections, and Basal Ganglia Encephalitis: Avery, 221
Case Studies: Tics and Antioxidants: Caleb, 244, 245
Methylenetetrahydrofolate reductase (MTHFR)
The PANS/PANDAS Journey: Laboratory Tests, 6
The PANS/PANDAS Journey: Considering PANDAS, 20
Meet the Infectious Agents: Mycoplasma and PANS, 47
Symptom-Specific Treatment: Anxiety, 133
294
Nancy O’Hara, MD, MPH, FAAP
Symptom-Specific Treatment: Tics, 141
Case Studies: Multiple Infections, Vitamin Deficiency, and Mycotoxins: Sofia, 217
Case Studies: Lyme, Multiple Co-Infections, and Basal Ganglia Encephalitis: Avery, 221
Methylmalonic Acid (MMA)
The PANS/PANDAS Journey: Laboratory Tests, 6
Meet the Infectious Agents: Other Infections: Parasites, Clostridia, Lyme Disease, and
Co-infections, 81, 82
Case Studies: Mitochondrial Dysfunction and Mycoplasma: Elijah, 212
Case Studies: Tics and Antioxidants: Caleb, 243
5-methyltetrahydrofolate (MTHF/5-MeTHF/Folinic acid)
The PANS/PANDAS Journey: Laboratory Tests, 6
The PANS/PANDAS Journey: Considering PANDAS, 20
Meet the Infectious Agents: Mycoplasma and PANS, 47
Symptom-Specific Treatment: Anxiety, 133
Symptom-Specific Treatment: Tics, 141
Case Studies: Mitochondrial Dysfunction and Mycoplasma: Elijah, 212
Case Studies: Multiple Infections, Vitamin Deficiency, and Mycotoxins: Sofia, 217
